Posted by: mericonpharma | July 31, 2011

Vitamin D Relieves Musculoskeletal Pain in Breast Cancer Patients Read more: Vitamin D Relieves Musculoskeletal Pain in Breast Cancer Patients | MedIndia http://www.medindia.net/news/Vitamin-D-Relieves-Musculoskeletal-Pain-in-Breast-Cancer-Patients


Vitamin D Relieves Musculoskeletal Pain in Breast Cancer Patients
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For many breast cancer patients who are taking estrogen-lowering drugs, high dose of vitamin D alleviates joint and muscle pain, reveals study from Washington University School of Medicine in St. Louis.

The drugs, known as aromatase inhibitors, are commonly prescribed to shrink breast tumors fueled by the hormone estrogen and help prevent cancer recurrence. They are less toxic than chemotherapy, but for many patients, the drugs may cause severe musculoskeletal discomfort, including pain and stiffness in the hands, wrists, knees, hips, lower back, shoulders and feet.

About half of patients can experience these symptoms, says Antonella L. Rastelli, MD, assistant professor of medicine and first author of the study published online in the journal Breast Cancer Research and Treatment. We don’t know exactly why the pain occurs, but it can be very debilitating — to the point that patients decide to stop taking aromatase inhibitors.

Because the drugs reduce cancer recurrence, finding a way to help patients stay on them is important for long-term, relapse-free survival, according to Rastelli. Aromatase inhibitors are prescribed to post-menopausal women for at least five years and often longer after a breast cancer diagnosis. There is some evidence that patients who experience the drugs’ side effects are less likely to see their cancer return, providing even more incentive to help these patients continue taking them.

It was Rastelli’s colleague, Marie E. Taylor, MD, assistant professor of radiation oncology, who first noticed that patients on aromatase inhibitors who experienced this pain found some relief from high doses of vitamin D.

Read more: Vitamin D Relieves Musculoskeletal Pain in Breast Cancer Patients | MedIndia http://www.medindia.net/news/Vitamin-D-Relieves-Musculoskeletal-Pain-in-Breast-Cancer-Patients-88297-1.htm#ixzz1TimBiVEA
Vitamin D Relieves Musculoskeletal Pain in Breast Cancer Patients

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